How to Use an Automatic Capsule-Filling Machine ?

Find the latest Blogs news from Canaan
Blog - How to Use an Automatic Capsule-Filling Machine ?
Canaan

How to Use an Automatic Capsule-Filling Machine ?

Using a capsule-filling machine can streamline your production process, whether you’re working in pharmaceuticals or supplement manufacturing. These machines can handle a variety of capsule materials like powders, granules, and even liquids. 

Automatic capsule-filling machine from Canaan
Automatic capsule-filling machine from Canaan
Automatic capsule-filling machine from Canaan

In this post, we’ll cover how to use an automatic capsule-filling machine and the steps involved.

StepDescription
1. Prepare the MachineEnsure the machine is clean and correctly assembled. Choose the right capsule size, check that trays and hoppers are installed properly, and load raw materials into the hopper.
2. Load Empty CapsulesLoad empty capsules into the machine by separating the capsule caps from the bodies and positioning the bodies for filling. This process typically involves sorting and aligning capsules.
3. Set ParametersUse the machine’s interface to set necessary parameters, including fill volume for each capsule, filling speed, and enable or disable mixing functions if multiple substances are used.
4. Start the Filling ProcessBegin filling capsules; the dosing system dispenses material into empty capsules while tamping pins compress the material for consistent filling and to remove air pockets.
5. Reassemble the CapsulesAfter filling, the machine automatically reattaches the capsule caps to the bodies, sealing them securely to prevent leakage or contamination.
6. Inspect the CapsulesConduct quality control by inspecting capsules for defects such as underfilled or overfilled capsules, damaged or improperly sealed ones, and remove any defective capsules.
7. Capsule PolishingUse integrated capsule polishers to remove excess powder from the surfaces of filled and sealed capsules, ensuring they are clean and ready for packaging.

What is a Capsule-Filling Machine?

What is a capsule-filling machine? A capsule-filling machine automates the process of filling empty capsules with powders, granules, or other substances. This allows for consistency, speed, and precision in production. 

Capsule

These machines are invaluable for high-production environments. They eliminate the need for manual filling, which can be time-consuming and prone to errors.

Step-by-Step Guide: How to Use a Capsule-Filling Machine

Let’s break down how to use a capsule-filling machine step by step:

1. Prepare the Machine

Before starting, ensure the machine is clean and ready for use. Follow these steps:

  • Confirm the machine is assembled correctly.
  • Choose the right capsule size for your product.
  • Check that trays, hoppers, and compartments are properly installed.
  • Ensure the raw materials—powders, granules, or liquids—are loaded into the hopper.

Preparing the machine correctly is crucial for ensuring smooth operation throughout the entire process.

2. Load Empty Capsules

Load empty capsules into the machine. This process involves separating the capsule caps from the bodies and positioning the bodies for filling. Capsule-filling machines often include trays or compartments to handle the following:

  • Sorting and separating the capsule caps from the bodies.
  • Aligning the capsule bodies for filling.

This automatic process helps speed up production while ensuring capsules are correctly oriented for the next steps.

3. Set Parameters

Use the machine’s interface to set the necessary parameters. This step involves:

  • Setting the fill volume for each capsule.
  • Adjusting the speed of the filling process.
  • Enabling or disabling the mixing function (if using multiple substances).

These parameters ensure that each capsule is filled consistently with the correct amount of product, whether it’s powder, granules, or liquids.

4. Start the Filling Process

Once everything is set, the machine can begin filling the capsules. Here’s how it works:

  • The machine’s dosing system dispenses the material into the empty capsules.
  • Tamping pins compress the material to ensure consistent filling and remove any air pockets.

Automatic machines fill large quantities of capsules quickly, which is ideal for high-volume production. For more complex formulations, machines can be equipped to mix multiple ingredients within a single capsule.

Canaan capsule filling machine

5. Reassemble the Capsules

After the capsule bodies are filled, the machine automatically reattaches the capsule caps to the bodies. This step seals the capsules securely and prevents leakage or contamination. The reassembly process is automated and ensures each capsule is perfectly aligned and sealed.

6. Inspect the Capsules

Quality control is essential. After the filling and sealing process, inspect the capsules for any defects:

  • Check for underfilled or overfilled capsules.
  • Identify any damaged or improperly sealed capsules.
  • Remove any defective capsules.

Many machines come equipped with a capsule rejection system that automatically removes capsules that don’t meet quality standards.

7. Capsule Polishing

Once the capsules are filled and sealed, they may have some powder residue on their surfaces. Capsule polishers are often integrated into the machine to remove excess powder and ensure that each capsule is clean and ready for packaging.

Key Features of Capsule-Filling Machines

Here’s why capsule-filling machines like Canaan’s are so effective in high-production environments:

Speed

Automatic capsule-filling machines are incredibly fast, filling thousands of capsules per hour. This dramatically increases production efficiency compared to manual methods. Machines designed for large-scale production can process anywhere from 24,000 to 400,000 capsules per hour, making them ideal for pharmaceutical industries.

Accuracy

Each capsule is filled with a precise, pre-measured dose. This level of accuracy ensures uniformity across all capsules, which is especially important in pharmaceuticals where precise dosages are critical.

Hygiene

Because the entire process is automated, human contact with the capsules is minimized, reducing the risk of contamination. This makes capsule-filling machines perfect for environments that require strict hygiene standards, such as the pharmaceutical industry.

Minimal Downtime

Automatic machines are designed to run continuously with minimal downtime. They require little maintenance during operation, which allows for uninterrupted production over long periods.

How to Maximize Machine Efficiency

To get the best results from your capsule-filling machine, follow these tips:

  • Regular Maintenance

Regular cleaning and maintenance are vital for ensuring the machine functions properly. Remove product buildup from the filling components and check the machine for any signs of wear or damage.

  • Monitor Capsule Quality

Frequently inspect the capsules during production. Look for capsules that are improperly filled, damaged, or incorrectly sealed, and remove them to maintain product quality.

  • Choose the Right Machine for Your Needs

Select a machine that matches your production scale. Smaller machines are ideal for limited production runs, while larger machines can handle thousands of capsules per hour. Consider factors like production volume, capsule size, and the type of materials being filled when choosing a machine.

Types of Materials Used in Capsule Filling

Powders in capsule
granule in capsule
liquid in capsule

Capsule-filling machines are versatile and can handle different types of materials:

  • Powders: One of the most common materials for capsule filling. Machines can fill powders smoothly and consistently without clogging.
  • Granules: Granules allow for controlled release in certain types of capsules. Machines handle these with the same precision as powders.
  • Liquids: Some machines can fill capsules with liquids. Special equipment is used to prevent spillage or leakage during the process.
  • Combinations: Machines can also fill capsules with a combination of materials, such as powders and granules, offering flexibility in product formulation.

Validation and Compliance for Capsule-Filling Machines

Capsule-filling machines must meet regulatory standards to ensure safety and effectiveness. Validation documents are typically provided with the machines to confirm compliance:

Factory Acceptance Testing (FAT)

Before shipping, FAT verifies that the equipment meets the design and operational requirements. The documentation includes:

  • FAT protocols
  • Test results
  • Necessary maintenance or modifications

Site Acceptance Testing (SAT)

After installation, SAT ensures that the machine operates correctly in its intended environment. Documentation covers:

  • Installation checks
  • Test results to confirm the machine meets specifications

Installation Qualification (IQ)

This confirms that the machine is installed properly, including utilities and safety connections, ensuring readiness for operational testing.

Operational Qualification (OQ)

OQ ensures that the machine operates correctly under actual production conditions, confirming it meets performance standards.

Final Thoughts

Using a capsule-filling machine significantly enhances production efficiency in industries like pharmaceuticals. By automating the entire capsule-filling process, these machines ensure precision, consistency, and high-quality output. 

Why Choose Canaan for Your Capsule-Filling Machines?

Canaan’s automatic capsule-filling machines come with certifications, ensuring compliance with international safety, health, and quality standards. They confirm that our machines meet rigorous safety protocols and deliver reliable, high-quality performance. 

With Canaan’s machines, you can confidently manage large-scale production, knowing that every step—from capsule filling to sealing—is handled with precision and minimal risk of contamination.

For more information, visit our website or get in touch with us!

Resources

What Is Factory Acceptance Testing (FAT) & How Does It Work?

What is a Site Acceptance Test?

Installation Qualification (IQ)

IQ, OQ, PQ: A Quick Guide to Process Validation (Plus Free Resources)

How to Use A Capsule-Filling Machine

RELATED POSTS
November 15.2024
Aurore
How to Maintain Used Freeze-Dried Machines

What is lyophilization? Freeze-drying, or lyophilization, is an important process in the pharmaceutical industry. It helps preserve medicines, vaccines, and other sensitive products by removing moisture.  If you buy a used freeze-dried machine, it’s essential to take proper care of it. Proper maintenance will extend the machine’s life, improve efficiency, and ensure the safety and […]

Read More
November 15.2024
Aurore
8 Key Components of a Pharmaceutical Freeze Dryer

What is freeze-drying? Freeze drying, also called lyophilization, is a method used to preserve medicines, vaccines, and other sensitive products. It removes moisture from products, which helps them stay stable for longer.  In the pharmaceutical industry, freeze-drying is key to storing important products, like biologics and vaccines, without needing refrigeration. For freeze-drying to work, you […]

Read More
November 15.2024
Aurore
Freeze vs Spray Drying: Which Is The Better Choice?

In the pharmaceutical industry, two common methods for drying products are freeze-drying and spray-drying. These methods remove water from products like medicines and vaccines, making them last longer and easier to store.  But how do they work? And which one is better for different types of products? Let’s explore the differences between freeze-drying and spray-drying, […]

Read More