Top 10 Drug Manufacturers in the USA

​The United States hosts some of the world’s leading pharmaceutical companies, renowned for their innovation, extensive product portfolios, and significant contributions to global healthcare. 

Below is an overview of the top 10 drug manufacturers in the USA, highlighting their 2023 revenues and key areas of focus.

10 Most Trusted Drug Manufacturers in the US

#1. Johnson & Johnson

Revenue: $85.2 billion​

Overview: 

Johnson & Johnson operates across three main sectors: pharmaceuticals, medical devices, and consumer health. 

Its pharmaceutical division, Janssen, specializes in therapeutic areas such as oncology, immunology, and neuroscience.

#2. Pfizer

Revenue: $58.5 billion

Overview: 

Pfizer is a leading manufacturer of drugs, known for its extensive portfolio that includes vaccines, oncology, and internal medicine products. 

The company played a pivotal role in developing one of the first COVID-19 vaccines.

#3. Merck & Co.

Revenue: $60.1 billion​
Overview: 

Merck, known as MSD outside the USA, focuses on prescription medicines, vaccines, biologic therapies, and animal health products. 

Key areas include oncology, infectious diseases, and cardiometabolic disorders. ​

#4. AbbVie

Revenue: $54.3 billion​

Overview: 

AbbVie specializes in immunology, oncology, virology, and neuroscience. The acquisition of Allergan in 2020 expanded its portfolio to include aesthetics and eye care.

#5. Bristol Myers Squibb

Revenue: $45.0 billion​

Overview: 

Bristol Myers Squibb focuses on oncology, hematology, immunology, and cardiovascular diseases. The acquisition of Celgene in 2019 bolstered its oncology and immunology offerings. ​

#6. Amgen

Revenue: $54.3 billion​

Overview: 

Amgen is a biotechnology company specializing in therapeutics for oncology, cardiovascular disease, inflammation, and nephrology. Its commitment to biotechnology has positioned it as a leader in biologic therapies. ​

#7. Eli Lilly and Company

Revenue: $45.03 billion​

Overview: 

Eli Lilly focuses on neuroscience, endocrinology, oncology, and immunology. The company is recognized for its advancements in diabetes care and neuroscience. ​

#8. Gilead Sciences

Revenue: $28.75 billion

Overview: 

Gilead specializes in antiviral drugs, particularly for HIV/AIDS, hepatitis B, hepatitis C, and influenza. Its innovative therapies have transformed the treatment landscape for these diseases.

#9. Biogen

Revenue: $10.98 billion​

Overview: 

Biogen focuses on neurological diseases, including multiple sclerosis, Alzheimer’s disease, and spinal muscular atrophy. Its dedication to neuroscience has led to groundbreaking therapies in neurology. ​

#10. Moderna

Revenue: $18.47 billion​

Overview: 

Moderna is a biotechnology company specializing in messenger RNA (mRNA) therapeutics and vaccines. It gained prominence with its mRNA-based COVID-19 vaccine and continues to explore mRNA applications across various diseases. ​

Key Trends and Challenges in the U.S. Pharmaceutical Industry

Innovation and Research

These manufacturing pharma companies invest heavily in research and development to bring new therapies to market, addressing unmet medical needs.​

Regulatory Landscape

Navigating the complex regulatory environment requires adherence to stringent standards to ensure safety and efficacy.​

Market Competition

The pharmaceuticals factory landscape is highly competitive, with companies striving for leadership in various therapeutic areas.​

Global Health Challenges

Manufacturers of drugs play a crucial role in responding to global health crises, such as pandemics, by developing and distributing vaccines and treatments.​

Pharmaceuticals Factory: Conclusion

In summary, the United States is home to several leading pharmaceutical companies that significantly impact global healthcare through innovation, extensive research, and a commitment to addressing diverse medical needs.​

Resources:

The world’s biggest pharmaceutical companies: Top ten by revenue

The top 20 pharma companies by 2023 revenue