Semaglutide Tablets vs. Injection: Which Is Better for Weight Loss?

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Recent data from the World Health Organization say around 2.5 billion adults ages 18 years and above are overweight, including over 890 million adults living with obesity. To combat this alarming health problem, some turn to workout fads and treatments. But, are they effective? 

Others who want quick results turn to a miracle weight loss drug known as the semaglutide. Semaglutides can either be in the form of tablets or injectables. What is the difference between compounded semaglutide injections and pills? Find out in this comparative guide covering the following:

– Semaglutide tablets vs. injection

– Key differences with pros and cons

– Providing safe semaglutide drugs for your consumers

What Semaglutides Are

This is a treatment mainly for diabetes. It is used alongside diet and exercise, helping you control the level of sugar in your blood. It is also consumed to decrease the risk of heart attacks, stroke, and even demise in patients diagnosed with the second diabetes type, as well as obesity and cardiovascular illnesses. 

Semaglutides are polypeptides containing a linear sequence of 31 amino acids bound together by peptide linkages. In other words, they are agonists of glucagon-like peptide-1 receptors. They work by mimicking GLP-1 to boost the release of insulin when blood sugar is high, slowing down the instance of hunger and decreasing the person’s appetite. 

Semaglutide Tablets and Injections

Semaglutide can either be in injectable or oral tablet form. Both of them are taken in to manage the levels of a person’s sugar in their blood, particularly those suffering from the second diabetes type, but with proper diet and exercise. 

The injection form is a renowned treatment for stroke and heart attack. It is also used for weight loss among those who are overweight and diagnosed with obesity. With both forms contain the same ingredients, their differences are upon administration frequency, requirements for needles, and the timing of food consumption.

Semaglutide Tablets vs. Injection: Points of Comparison

Learn about these key differences between semaglutide tablets and injections: dosage timing, bioavailability, needle requirement, administration, and effectiveness. 

Dosage Timing

The tablet form is taken once every day, while the injections are administered once a week. Those who are constricted with their schedule, but can take a bit of pain can choose the injectable. 

Bioavailability

In terms of bioavailability, the oral form is at the lower range, compared to the injection. Therefore, a higher dose is required when you want the oral tablet to provide immediate, similar effects.

Needle Requirement

Injectable semaglutides use a pen device for the subcutaneous injections. 

Administration

Aside from taking it once per day, semaglutide tablets must be ingested 30 minutes before your day’s first food, beverage, or other medications. Pair a tablet with no more than four ounces of plain water. After the 30 minutes have lapsed, you may already eat, drink, or take other oral medicines.

Meanwhile, injectables of semaglutide are injected under the person’s skin, once per day at any point of the day, with or without food prior. But, remember to administer the injection on the same day each week as much as possible. 

Effectiveness and Cost

Are semaglutide tablets as effective as injections? The efficacy and safety of both the tablet and injection forms are generally the same. With occasional adjustments based on your needs and tolerability, some may already achieve significant benefits and control with just a low dosage of either form, while others may need to combine one with another treatment for more efficacy. The cost will depend on the brand you choose.

Pros and Cons of Oral and Injection Semaglutides

Oral Tablets

  • No needles required
  • Typically taken daily
  • Must be taken on an empty stomach first thing in the morning and fast for 30 minutes after
  • May have side effects

Injectables

  • Requires the use of needles
  • Taken once a week usually
  • It doesn’t matter if you’ve eaten before or after the injection
  • May also have side effects

Are There Side Effects?

Yes, both the oral tablet and injectable forms of semaglutide have side effects. For the oral tablets, the side effects feeling nauseous, vomiting, and pain in the abdominal area, among others. For the injectable, side effects include reactions around the injection site, such as tumors.

The Verdict

So, semaglutide tablets vs. injection, which is better? Well, both the tablet and injection semaglutides can effectively help with weight loss and diabetes treatment. However, the choice will depend on your lifestyle and how your body can tolerate the pain. Injectables require needles, but you won’t need to control your diet before and after the injection. The oral tablets are less painful but must be taken first thing in the morning on an empty stomach and you must not consume food half an hour after taking it.

Providing Safe Semaglutides for Your Consumers

Is your business providing semaglutide tablets for your consumers or clients? Ensure they are safe and effective by manufacturing them right. With Canaan’s wide range of innovative equipment for producing pharmaceutical products, you can ensure optimum value for the well-being of the people you care about. Find out more about Canaan’s solutions by coordinating with their team today.

Resources:

Semaglutide oral vs. injection

Semaglutide tablets vs. injection

Semaglutide – StatPearls – NCBI Bookshelf

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